Agenda
The full-day symposium will be broken into a morning and afternoon session. Breakfast and lunch will be served. Coffee and refreshments will be available throughout the day.
All Sessions
Morning Session – All times CET (UTC+1)
Breakfast Buffet & Coffee
Welcome Remarks
- Niranjan Bose, Interim Executive Director, AD Data Initiative
- Jane McIntosh, Interim CEO, Chief Philanthropy and External Affairs Officer, ADDF
Opening Keynote
- Henrik Zetterberg, Professor of Neurochemical Pathophysiology and Diagnostics, University of Gothenburg
Session 1: From Data to Insights on Sex/Gender Differences in Alzheimer’s Disease Risk
MODERATOR:
- Miia Kivipelto, Professor, Clinical Geriatrics, Karolinska Institute
PANELISTS:
- Shireen Sindi, Karolinska Institute
- Natalia Vilor-Tejedor, BarcelonaBeta Brain Research Center
- Laura Nisenbaum, ADDF
- Russ Paulsen, UsAgainstAlzheimer’s
This discussion will highlight the importance of diverse and interoperable data in driving progress and show how shared infrastructure and collaborative approaches to research transform fragmented data into key insights. This discussion will include a strong focus on the S|GN Consortium.
Coffee Break
Featured Spotlight: DxA 3.0
- Aishu Sukumar, Associate Director, Alzheimer’s Disease at Gates Ventures
This spotlight discussion will focus on the evolution of AD detection over the different stages, the progression of the DxA focus to align with the shift in the field and utilizing DxA 3.0 to leverage the advancing diagnostic technologies and AI capabilities. These advances will continue to push the envelope to capture disease heterogeneity and expand to other contexts of use to get a better picture of an individual’s disease trajectory and therapeutic response.
Session 2: Capturing Disease Heterogeneity
MODERATOR:
- Laura Nisenbaum, Executive Director of Drug Development, ADDF
PANELISTS:
- Henrik Zetterberg, University of Gothenburg
- Manu Vandijck, Fujirebio
- Carrie Ruble, Biogen
- Miranda Orr, Washington University at St Louis
- Niklas Mattsson-Carlgren, Lund University
- Erez Eitan, NeuroDex
This panel discussion highlights the value of moving beyond amyloid-centric frameworks to capture the biological complexity underlying disease heterogeneity, focusing on efforts to date, strategies for leveraging existing datasets, key challenges, and paths forward to enable the next generation of diagnostics.
Networking Lunch
Afternoon Session – All times CET (UTC+1)
Coffee Break
Alzheimer’s Insights AI Prize | Finalist Pitch Event (Livestreamed)
JUDGES:
- Greg Moore, Sr. Advisor, Gates Ventures (Moderator)
- Justine Levin-Allerhand, Flagship Labs, Flagship Pioneering
- Aashima Gupta, Google Cloud
- Elena Bonfiglioli, Microsoft
- Zoe Kourtzi, University of Cambridge
FINALIST TEAMS:
- Aletheia
- Biomni-AD
- corteX
- Fingerprint
- PrimaMente
Five finalist teams present their agentic AI solutions designed to accelerate Alzheimer's and related dementias research. Each team demonstrates scalable, interoperable approaches that align with the Alzheimer's Disease Data Initiative's platforms and mission to serve the public good.
Session 3 – Featured Spotlight: SpeechDx
- Melissa Lee, Director of the Diagnostics Accelerator, ADDF
This spotlight talk will highlight current updates for SpeechDx projects
Session 3: Understanding Risk, Prevention and Early Signals
MODERATOR:
- Rhoda Au, Professor of Anatomy & Neurobiology, Neurology, Medicine and Epidemiology at Boston University Chobanian & Avedisian School of Medicine and School
PANELISTS:
- Jim Uzgiris, Siemens, SpeechDx and AI
- David Berron, neotiv
- Lampros Kourtis, Gates Ventures
- Melissa Lee, Diagnostics Accelerator, ADDF
This panel discussion will focus on the earliest points of intervention and the importance of representative, multimodal data. The panel will discuss key topics related to leveraging AI for the development of digital tools for AD, biology of risk & resilience, the role of speech, eye tracking, sleep, behavior, active/passive digital and other biomarkers in early detection, and translating population level insights into individual recommendations.
Closing Remarks
- Niranjan Bose, Interim Executive Director, AD Data Initiative
- Laura Nisenbaum, Executive Director of Drug Development, ADDF
Morning Session
Breakfast Buffet & Coffee
Welcome Remarks
- Niranjan Bose, Interim Executive Director, AD Data Initiative
- Jane McIntosh, Interim CEO, Chief Philanthropy and External Affairs Officer, ADDF
Opening Keynote
- Henrik Zetterberg, Professor of Neurochemical Pathophysiology and Diagnostics, University of Gothenburg
Session 1: From Data to Insights on Sex/Gender Differences in Alzheimer’s Disease Risk
MODERATOR:
- Miia Kivipelto, Professor, Clinical Geriatrics, Karolinska Institute
PANELISTS:
- Shireen Sindi, Karolinska Institute
- Natalia Vilor-Tejedor, BarcelonaBeta Brain Research Center
- Laura Nisenbaum, ADDF
- Russ Paulsen, UsAgainstAlzheimer’s
This discussion will highlight the importance of diverse and interoperable data in driving progress and show how shared infrastructure and collaborative approaches to research transform fragmented data into key insights. This discussion will include a strong focus on the S|GN Consortium.
Coffee Break
Featured Spotlight: DxA 3.0
- Aishu Sukumar, Associate Director, Alzheimer’s Disease at Gates Ventures
This spotlight discussion will focus on the evolution of AD detection over the different stages, the progression of the DxA focus to align with the shift in the field and utilizing DxA 3.0 to leverage the advancing diagnostic technologies and AI capabilities. These advances will continue to push the envelope to capture disease heterogeneity and expand to other contexts of use to get a better picture of an individual’s disease trajectory and therapeutic response.
Session 2: Capturing Disease Heterogeneity
MODERATOR:
- Laura Nisenbaum, Executive Director of Drug Development, ADDF
PANELISTS:
- Henrik Zetterberg, University of Gothenburg
- Manu Vandijck, Fujirebio
- Carrie Ruble, Biogen
- Miranda Orr, Washington University at St Louis
- Niklas Mattsson-Carlgren, Lund University
- Erez Eitan, NeuroDex
This panel discussion highlights the value of moving beyond amyloid-centric frameworks to capture the biological complexity underlying disease heterogeneity, focusing on efforts to date, strategies for leveraging existing datasets, key challenges, and paths forward to enable the next generation of diagnostics.
Networking Lunch
Afternoon Session
Session 3 – Featured Spotlight: SpeechDx
- Melissa Lee, Director of the Diagnostics Accelerator, ADDF
This spotlight talk will highlight current updates for SpeechDx projects
Session 3: Understanding Risk, Prevention and Early Signals
MODERATOR:
- Rhoda Au, Professor of Anatomy & Neurobiology, Neurology, Medicine and Epidemiology at Boston University Chobanian & Avedisian School of Medicine and School
PANELISTS:
- Jim Uzgiris, Siemens, SpeechDx and AI
- David Berron, neotiv
- Lampros Kourtis, Gates Ventures
- Melissa Lee, Diagnostics Accelerator, ADDF
This panel discussion will focus on the earliest points of intervention and the importance of representative, multimodal data. The panel will discuss key topics related to leveraging AI for the development of digital tools for AD, biology of risk & resilience, the role of speech, eye tracking, sleep, behavior, active/passive digital and other biomarkers in early detection, and translating population level insights into individual recommendations.
Coffee Break
Alzheimer’s Insights AI Prize | Finalist Pitch Event (Livestreamed)
JUDGES:
- Greg Moore, Sr. Advisor, Gates Ventures (Moderator)
- Justine Levin-Allerhand, Flagship Labs, Flagship Pioneering
- Aashima Gupta, Google Cloud
- Elena Bonfiglioli, Microsoft
- Zoe Kourtzi, University of Cambridge
FINALIST TEAMS:
- Aletheia
- Biomni-AD
- corteX
- Fingerprint
- PrimaMente
Five finalist teams present their agentic AI solutions designed to accelerate Alzheimer's and related dementias research. Each team demonstrates scalable, interoperable approaches that align with the Alzheimer's Disease Data Initiative's platforms and mission to serve the public good.
Closing Remarks
- Niranjan Bose, Interim Executive Director, AD Data Initiative
- Laura Nisenbaum, Executive Director of Drug Development, ADDF

